U-M Center for Integrative Research in Critical Care

U-M Center for Integrative Research in Critical Care

The U-M Center for Integrative Research in Critical Care (MCIRCC) journey started nearly three years ago with one aspirational vision: To transform critical care medicine for improved patient care and outcomes by accelerating science and moving it from bench to bedside. To accomplish this, MCIRCC unifies scientists, clinicians, engineers, industry partners and funding streams to develop and deploy solutions that restore patient health.

Team science

Because of the fast pace and complexity of critical care, many of the most important problems can only be solved by multidisciplinary research teams. At the same time, funding opportunities are increasing for large-scale, team-driven research that tackles complex problems like critical care with transformative solutions. This has created a target-rich environment that MCIRCC exploits using its integrated team science model.


U-M and NCRC provide the ideal environment for MCIRCC to assume an elite position among academic institutions in bringing university-led critical care innovations to market. The MCIRCC Catalyst (see sidebar) has developed a strong commercialization-focused infrastructure to amplify innovation and prioritize research aimed at rapid translation from bench to bedside via the following strategies:

  • team science rooted in clinical and market relevance
  • alignment with FDA regulatory considerations and commercialization pathways
  • early integration strategies with industry, entrepreneurs and donors
  • emphasizing platform technologies for impact across the spectrum of care

Pete Tchoryk, CEO of MCIRCC partner SpringMatter, confirms the efficacy of the Catalyst. “We work with a large number of academic research institutions, and I can safely say that we have never encountered a center that unites all the stakeholders in the community so effectively.  The power and uniqueness of MCIRCC, as we see it, is their ability to focus the energy and passion of the medical, engineering, academic, government, donor, and industrial communities to a single purpose.”

Elevating patient care at reduced cost

The fast pace and complexity of critical care make it ripe for transformative change using advanced technology solutions. Forthcoming healthcare reform and market shifts will further stress the patient care delivery system, requiring health systems to respond and adapt via innovative and disruptive solutions to stay relevant and ahead of the competition. UMHS is in a position to dominate the marketplace in the creation and testing of such solutions that elevate patient care at a reduced cost.

MCIRCC seeks to bridge the gap between clinical experts, research masterminds, industry partners and technological advances to transform critical care delivery using data in motion and cognitive computing to improve patient outcomes at reduced costs by way of the following strategies:

  • Deploy big data analytic platform to elevate value of analytics portfolio via agile research, development and testing
  • Blend clinical expertise with predictive analytics and cognitive computing to develop clinical decision support tools
  • Utilize advanced analytics to deliver personalized and evidence-based medicine in UMHS test beds
  • Harness ultra-high fidelity clinical data and physiologic waveform for data in motion phenotyping
  • "We work with a large number of academic research institutions, and I can safely say that we have never encountered a center that unites all the stakeholders in the community so effectively."
    Pete Tchoryk, CEO of SpringMatter

MCIRCC’s Mission

To bring together world-class expertise and create partnerships throughout U-M and with external partners to develop and deploy critical care solutions that are precise, predictive, proactive, and personalized for real world impact.

  • “With proper focus on the intersection of clinical, business, and technology domains we can innovate rapidly together.”
    Matt Patterson, CEO of AirStrip

The MCIRCC Catalyst


With a membership base comprised of more than 100 world-class researchers from seven U-M schools and colleges, MCIRCC has made tremendous headway thanks in part to the MCIRCC Catalyst–the framework that integrates its unique combination of assets including operational structures, membership programs and technology systems to execute MCIRCC’s vision in a scalable design.


The result is the creation of a new, innovative business model at U-M for the academic research enterprise that provides end-to-end management of the research pipeline. MCIRCC’s performance over the past year has proven this model to be efficient, cost effective and nimble.


Every discussion and future-state prediction about transforming healthcare involves data analytics. Paired with advanced technology, big data–or what MCIRCC likes to call the “right data”–is an important facet of MCIRCC’s brand, and integral to their future success and sustainability.


This vision leads MCIRCC to: push research beyond the idea stage, for real world impact; create groundbreaking new technologies, products, and services; and help researchers and industry partners commercialize their innovations.

Untapped benefactors influence science and discovery

Disruptive solutions using advanced technology appeal to a unique, untapped pool of sophisticated benefactors willing to contribute their entrepreneurial expertise, passion, and financial support to find high-impact, real-world solutions. MCIRCC cultivates new funding sources for high-risk, high-reward discovery work and translational research by offering government agencies, donors and strategic industry leaders a seat at the table:


  • Offer mechanisms that allow benefactors to provide iterative and positive feedback to drive exploration, impact and output in critical care
  • Measure success based on products delivered to market that improve patient outcomes at reduced costs
  • Develop marketing communications that engage the “right” donors and industry partners for financial and resource support of key initiatives


Another MCIRCC partner, AirStrip CEO Matt Patterson, says, “There is tremendous alignment of vision and mission between AirStrip and MCIRCC. With proper focus on the intersection of clinical, business, and technology domains we can innovate rapidly together to create clinician workflows in healthcare that are a must-have to thrive in an increasingly challenging economic landscape.

AirStrip sees the University of Michigan as a standard bearer of trusted and credible leaders in academic medicine. To see that combined with a visionary arm like MCIRCC that is also capable of executing at an industry pace is a dynamic combination that is often touted by others but rarely lives up to its billing.”

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